Tincture of Opium

Tincture of opium crossword clue. A crossword question on 30 May 2017, 8 letters.

The answer is LAUDANUM

Laudanum is a tincture of opium containing approximately 10% powdered opium by weight (the equivalent of 1% morphine).

Reddish-brown and extremely bitter, laudanum contains almost all of the opium alkaloids, including morphine and codeine, and its high morphine concentration makes it a potent narcotic. Laudanum was historically used to treat a variety of ailments, but its principal use was as an analgesic and cough suppressant. Until the early 20th century, laudanum was sold without a prescription and was a constituent of many patent medicines. Today, laudanum is recognized as addictive and is strictly regulated and controlled as such throughout most of the world. The United States Uniform Controlled Substances Act, for one example, lists it on Schedule II.

Laudanum is known as a “whole opium” preparation since it historically contained all the opium alkaloids. Today, however, the drug is often processed to remove all or most of the noscapine (also called narcotine) present as this is a strong emetic and does not add appreciably to the analgesic or anti-propulsive properties of opium; the resulting solution is called Denarcotized Tincture of Opium or Deodorized Tincture of Opium (DTO).